Which term is the delivery of drug to the intended organ after it was absorbed?

Which term is the delivery of drug to the intended organ after it was absorbed?

• A. Absorption
• B. Exertion
• C. Distribution
• D. Sources of drugs

Answer: (C)

Distribution is the delivery of the drug from the bloodstream to the intended organ after absorption. After a drug is absorbed, it travels with the circulating blood to tissues, and how much reaches a target organ and how fast it gets there depends on regional blood flow, the drug’s ability to cross membranes, and how it binds to plasma proteins or tissue components. Only the unbound portion can diffuse into cells and produce effects, so binding can slow distribution and influence duration of action. Lipophilic drugs tend to distribute more widely, potentially reaching the brain or fatty tissues, while hydrophilic drugs stay more in the vascular compartment. After distribution comes metabolism and excretion, which clear the drug from the body. Absorption occurs before distribution, exertion isn’t a pharmacology term, and sources of drugs refer to origins rather than delivery to the organ.

Distribution is the delivery of the drug from the bloodstream to the intended organ after absorption. After a drug is absorbed, it travels with the circulating blood to tissues, and how much reaches a target organ and how fast it gets there depends on regional blood flow, the drug’s ability to cross membranes, and how it binds to plasma proteins or tissue components. Only the unbound portion can diffuse into cells and produce effects, so binding can slow distribution and influence duration of action. Lipophilic drugs tend to distribute more widely, potentially reaching the brain or fatty tissues, while hydrophilic drugs stay more in the vascular compartment. After distribution comes metabolism and excretion, which clear the drug from the body. Absorption occurs before distribution, exertion isn’t a pharmacology term, and sources of drugs refer to origins rather than delivery to the organ.