Which antibiotic class is commonly associated with photosensitivity, requiring sun protection advice?

Which antibiotic class is commonly associated with photosensitivity, requiring sun protection advice?

• A. Macrolides
• B. Fluoroquinolones
• C. Aminoglycosides
• D. Glycopeptides

Answer: (B)

Photosensitivity from antibiotics occurs when a drug makes the skin more reactive to UV light, leading to sunburn-like reactions after sun exposure. This effect is most commonly seen with fluoroquinolones. Meds in this class, such as ciprofloxacin and levofloxacin, can cause redness, itching, and even blistering on sun-exposed skin after only brief exposure. Because of this risk, patients taking these antibiotics should take sun-protection steps: use broad-spectrum sunscreen, wear protective clothing and hats, seek shade, and avoid tanning beds. If a severe skin reaction develops, contact a clinician promptly. Other antibiotic classes listed are less likely to cause photosensitivity, so the sun-protection emphasis is specifically important with fluoroquinolones.

Photosensitivity from antibiotics occurs when a drug makes the skin more reactive to UV light, leading to sunburn-like reactions after sun exposure. This effect is most commonly seen with fluoroquinolones. Meds in this class, such as ciprofloxacin and levofloxacin, can cause redness, itching, and even blistering on sun-exposed skin after only brief exposure. Because of this risk, patients taking these antibiotics should take sun-protection steps: use broad-spectrum sunscreen, wear protective clothing and hats, seek shade, and avoid tanning beds. If a severe skin reaction develops, contact a clinician promptly. Other antibiotic classes listed are less likely to cause photosensitivity, so the sun-protection emphasis is specifically important with fluoroquinolones.